PROTAC IRAK4 degrader-3 (Synonyms: PROTAC IRAK4 degrader-3) |
| Katalog-Nr.GF04051 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2374122-43-5
Sample solution is provided at 25 µL, 10mM.
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PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.
PROTAC IRAK4 degrader-3 (0.01~10 渭M; 2 hours; PBMCs) mediated degradation is occurring in a proteasome dependent manner[1].
PROTAC IRAK4 degrader-3 (0.01~100 渭M; 18 hours; PBMCs) is capable of completely blocking IL-6 secretion[1].
[1]. Nunes J, et al. Targeting IRAK4 for Degradation with PROTACs. ACS Med Chem Lett. 2019;10(7):1081-1085. Published 2019 Jun 14.
Review for PROTAC IRAK4 degrader-3
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for PROTAC IRAK4 degrader-3
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