Harringtonolide (Synonyms: Harringtonolide) |
| Katalog-Nr.GF11045 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 64761-48-4
Sample solution is provided at 25 µL, 10mM.
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Harringtonolide (0-50 渭M; 24 hours) exhibits good antiproliferation activity in A375 cells with IC50 of 39.66 渭M[1].
Harringtonolide (0-20 渭M; 1 hour) restrains the proteolysis of RACK1 by Pronase, and protects temperature-dependent degradation of RACK1[1].
Harringtonolide (0-4 渭M; 24 hours) suppresses the phosphorylation of FAK dose-dependently and inhibits Src and STAT3, the downstream proteins of FAK[1].
Harringtonolide (0-4 渭M; 24 hours) dose-dependently inhibits the RACK1鈥揊AK interaction in A375 cells[1].
[1]. Zhu TY, et al. Photoaffinity Probe Reveals the Potential Target of Harringtonolide for Cancer Cell Migration Inhibition. ACS Med Chem Lett. 2022;13(3):449-456. Published 2022 Feb 2.
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