1-((4-Nitrophenyl)sulfonyl)piperidine |
| Katalog-Nr.GF47600 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 64268-93-5
Sample solution is provided at 25 µL, 10mM.
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VP-4604 (2.5 mM, 18 hours) inhibits drug-resistant S. aureus and P. aeruginosa with growth inhibiton (%) GI >95%[1].
VP-4604 shows low cytotoxicity with a CC50 value >118.4 mM towards HEK-293 (human embryonic kidney) ATCC CRL鈥?573 and an HC10 vaule >118.4 渭M towards RBC (human red blood cells) [1].
VP-4604 (2.5 mM) is tolerated by mammalian cells (HaCaT, lymphocytes) with the inhibition growth (%) of 44.1% and >50%, respectively[1].
[1]. Vitalii Palchykov, et al. Antimicrobial action of arylsulfonamides bearing (aza)norbornane and related motifs: evaluation of new promising anti-MRSA agents. Medicinal Chemistry Research. 2022. 31: 284-292.
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