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Glycol salicylate

Katalog-Nr.GC30336

Glykolsalicylat ist ein Derivat der SalicylsÄure und kann verwendet werden, um das Ästhetische Erscheinungsbild der Haut zu verbessern, extrahiert aus dem Patent US 20150148320 A1.

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Glycol salicylate Chemische Struktur

Cas No.: 87-28-5

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10mM (in 1mL DMSO)
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5g
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Sample solution is provided at 25 µL, 10mM.

Description of Glycol salicylate

Glycol salicylate is a derivative of salicylic acid and can be used to improve the aesthetic appearance of the skin, extracted from patent US 20150148320 A1.

[1]. Kai Xi, et al. Cosmetic use of salicylic acid derivatives. US 20150148320 A1.

Chemical Properties of Glycol salicylate

Cas No. 87-28-5 SDF
Canonical SMILES O=C(OCCO)C1=CC=CC=C1O
Formula C9H10O4 M.Wt 182.17
Löslichkeit DMSO : 160 mg/mL (878.30 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Glycol salicylate

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 5.4894 mL 27.4469 mL 54.8938 mL
5 mM 1.0979 mL 5.4894 mL 10.9788 mL
10 mM 0.5489 mL 2.7447 mL 5.4894 mL
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Berechnen

In vivo Formulation Calculator (Clear solution) of Glycol salicylate

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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