GS-441524 HCl (Synonyms: GS-441524 HCl; GS-441524 hydrochloride; GS-441524; GS441524; GS 441524; Remdesivir-metabolite, GS-5734-metabolite; GS5734-metabolite; GS 5734-metabolite;) |
| Katalog-Nr.GB62257 |
GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an EC50 of 0.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2378280-82-9
Sample solution is provided at 25 µL, 10mM.
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GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an EC50 of 0.78 μM.. GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. GS-441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. GS-441524 was non-toxic in feline cells at concentrations as high as 100?uM and effectively inhibited FIPV replication in cultured CRFK cells and in naturally infected feline peritoneal macrophages at concentrations as low as 1 uM. Note: GS-441524 is an active metabolite of Remdesivir.
Review for GS-441524 HCl
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for GS-441524 HCl
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