GSK J2 |
| Katalog-Nr.GC13086 |
GSK J2 ist ein Isomer von GSK-J1, das keine spezifische Aktivität aufweist. GSK-J1 ist ein potenter Inhibitor der H3K27me3/me2-Demethylasen JMJD3/KDM6B und UTX/KDM6A.
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Cas No.: 1394854-52-4
Sample solution is provided at 25 µL, 10mM.
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GSK-J2 is an isomer of GSK-J1 that does not have any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.
GSK-J2 is an isomer of GSK-J1, and shows poor activity towards KDM6A and KDM6B, with IC50 of > 100 μM and 49 μM, respectively[1].
References:
[1]. Heinemann B, et al. Inhibition of demethylases by GSK-J1/J4. Nature. 2014 Oct 2;514(7520):E1-2.
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