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H3B-120

Katalog-Nr.GC39648

H3B-120 ist ein hochselektiver, kompetitiver und allosterischer Inhibitor der Carbamoylphosphat-Synthetase 1 (CPS1) mit einem IC50 von 1,5 μM und einem Ki von 1,4 μM. H3B-120 hat Anti-Krebs-AktivitÄt.

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H3B-120 Chemische Struktur

Cas No.: 2194903-42-7

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

H3B-120 is a highly selective, competitive and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor with an IC50 of 1.5 μM and a Ki of 1.4 μM. H3B-120 has anti-cancer activity[1].

[1]. Yao S, et al. Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. Cell Chem Biol. 2020 Mar 19;27(3):259-268.

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