Hydroxy Desmethyl Bosentan (Synonyms: Ro 64-1056) |
| Katalog-Nr.GC49175 |
Hydroxy-Desmethyl-Bosentan (Ro 64-105) ist ein Bosentan-Metabolismus, der von den Cytochrom-P450-Enzymen CYP2C9 und CYP3A4 in der Leber produziert wird.
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Cas No.: 253688-62-9
Sample solution is provided at 25 µL, 10mM.
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Hydroxy desmethyl bosentan is a metabolite of the endothelin receptor antagonist bosentan .1
1.van Giersbergen, P.L.M., Gnerre, C., Treiber, A., et al.Bosentan, a dual endothelin receptor antagonist, activates the pregnane X nuclear receptorBr. J. Clin. Pharmacol.54(5)561-562(2002)
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