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Irsenontrine (Synonyms: E2027)

Katalog-Nr.GC65911

Irsenontrin (E2027) ist ein oral aktiver und selektiver Phosphodiesterase 9 (PDE9)-Hemmer. Irsenontrin kann zur Erforschung neurologischer Erkrankungen eingesetzt werden.

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Irsenontrine Chemische Struktur

Cas No.: 1429509-82-9

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Irsenontrine (E2027) is an orally active and selective phosphodiesterase 9 (PDE9) inhibitor. Irsenontrine can be used for the research of neurological diseases[1][2][3].

Irsenontrine (E2027) is an orally active and selective phosphodiesterase 9 (PDE 9) inhibitor[3].

Irsenontrine (0.3, 3.3 mg/kg; p.o.) exhibits a significant ameliorative effect on the percentage of exploration of the novel object at 3.3 mg/kg in Scopolamine-induced rats[1].
Irsenontrine (1 mg/kg; p.o.) and memantine hydrochloride (1 mg/kg; p.o.) combined treatment group exhibits a significantly higher percentage of exploration of the novel object than memantine hydrochloride (1 mg/kg) alone[1].

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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