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Ischemin sodium

Katalog-Nr.GC70314

Ischemin sodium ist ein CBP-Bromodom-Inhibitor, der die p53-Interaktion mit CBP und die Transkriptionsaktivität in Zellen hemmt.

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Ischemin sodium Chemische Struktur

Größe Preis Lagerbestand Menge
5 mg
231,00 $
Auf Lager
10 mg
365,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Ischemin sodium is a CBP bromodomain inhibitor that inhibits p53 interaction with CBP and transcriptional activity in cells. Ischemin sodium salt inhibits p53-induced p21 activation with an IC50 value of 5 µM. Ischemin sodium salt also prevents apoptosis in ischemic cardiomyocytes. Ischemin sodium salt can be used in the study of cardiovascular diseases (such as myocardial ischemia).

Ischemin sodium (50, 100 µM; 24 h) inhibits p53 activation on DNA damaging stress in U2OS cells[1].
Ischemin sodium (10 μM; 3 days) blocks apoptosis in cardiomyocytes by inhibiting caspase 3/7 activity[1].
Ischemin sodium salt inhibits p53 cellular signaling pathways in U2OS cells[1].

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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