Isoprocurcumenol |
| Katalog-Nr.GC70377 |
Isoprocurcumenol ist ein Sesquiterpen vom Typ Guaiane, das aus Curcuma comosa isoliert werden kann.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 102130-90-5
Sample solution is provided at 25 µL, 10mM.
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Isoprocurcumenol (10 μM, 0-1 h) increases the phosphorylation of ERK and AKT[3].
Isoprocurcumenol (0-200 μM, 24 or 48 h) induces the proliferation of keratinocytes HaCaT cells[3].
Isoprocurcumenol (1 μM, 1 h) increases the expression of genes related to cell growth and proliferation, such as c-fos, c-jun, c-myc, and egr-1, through activation of the EGFR signaling pathway[3].
Isoprocurcumenol induces cell recovery and wound healing[3].
References:
[1]. Qu Y, et al. Sesquiterpenes from Curcuma comosa. J Nat Med. 2009 Jan;63(1):102-4.
[2]. Anuchapreeda S, et al. Cytotoxicity and inhibition of leukemic cell proliferation by sesquiterpenes from rhizomes of Mah-Lueang (Curcuma cf. viridiflora Roxb.). Bioorg Med Chem Lett. 2018 Feb 1;28(3):410-414.
[3]. Kwon PK, et al. Isoprocurcumenol Supports Keratinocyte Growth and Survival through Epidermal Growth Factor Receptor Activation. Int J Mol Sci. 2021 Nov 22;22(22):12579.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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