J27644 |
Katalog-Nr.GC91389 |
J27644 ist ein Inhibitor der Histondeacetylase 6 (HDAC6; IC50 = 10 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
J27644 is an inhibitor of histone deacetylase 6 (HDAC6; IC50 = 10 nM).1 It is selective for HDAC6 over HDAC1-5 (IC50s = 211-516 nM) and HDAC7, -8, -9, and -11 (IC50s = 137-812 nM). J27644 (10 µM) reduces the level of proteins involved in fibrosis, including collagen 1A1, α-smooth muscle actin (α-SMA), and fibronectin, in human pulmonary fibroblasts in vitro.
Review for J27644
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)Review for J27644
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