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L-Kynurenine-13C10 sulfate hemihydrate

Katalog-Nr.GC70236

L-Kynurenine-13C10 sulfate hemihydrate ist das 13C markierte L-Kynureninsulfat.

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L-Kynurenine-13C10 sulfate hemihydrate Chemische Struktur

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100 µg
378,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
L-Kynurenine-13C10 (sulfate hemihydrate) is the 13C labeled L-Kynurenine sulfate. L-Kynurenine sulfate hemihydrate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype.

References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[2]. Benjamin J Moyer, et al. Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1. Toxicol Appl Pharmacol. 2016 Jun 1;300:13-24.

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