Lenampicillin hydrochloride (KBT 1585 hydrochloride) |
| Katalog-Nr.GC34147 |
Lenampicillin-Hydrochlorid (KBT 1585-Hydrochlorid) (KBT 1585-Hydrochlorid) ist ein oral aktives Prodrug von Ampicillin und ein wirksames Beta-Lactam-Antibiotikum, das bakterielle Penicillin-bindende Proteine (Transpeptidase) hemmt. Lenampicillin-Hydrochlorid (KBT 1585-Hydrochlorid) hat im Vergleich zu Ampicillin eine verbesserte Resorption und verringerte Nebenwirkungen und wird zur Untersuchung der eitrigen Haut- und Weichteilinfektion eingesetzt.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 80734-02-7
Sample solution is provided at 25 µL, 10mM.
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Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.
[1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93. [2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84.
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