Lipid Catechol |
| Katalog-Nr.GC90964 |
Ein Lipid, das bei der Bildung von Lipid-Prodrug-Nanoassemblies verwendet wird.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2930813-52-6
Sample solution is provided at 25 µL, 10mM.
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Lipid catechol is a lipid that contains an α-aminophosphonate group, two 14-carbon acyl chains, and a catechol ring that forms a covalent bond with boronic acid-containing compounds to form lipid prodrug nanoassemblies (LPNA).1 LPNAs composed of lipid catechol conjugated to phenylboronic acid-modified ciprofloxacin (CIP-PBA) inhibit the formation of, and disrupt preformed, S. aureus biofilms and eradicate staplococci in a mouse model of peritoneal S. aureus infection. LPNAs composed of lipid catechol conjugated to bortezomib (BTZ) reduce tumor growth and increase survival in a 4T1 murine mammary carcinoma model.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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