m-PEG3-CH2CH2COOH |
| Katalog-Nr.GC66154 |
m-PEG3-CH2CH2COOH ist ein nicht spaltbarer ADC-Linker, der bei der Synthese von AntikÖrper-Wirkstoff-Konjugaten (ADCs) verwendet wird. m-PEG3-CH2CH2COOH ist ebenfalls ein PEG-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 67319-28-2
Sample solution is provided at 25 µL, 10mM.
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m-PEG3-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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