Maleic hydrazide |
| Katalog-Nr.GC60234 |
MaleinsÄurehydrazid wird in großem Umfang als systemischer Pflanzenwachstumsregulator und als Herbizid verwendet. MaleinsÄurehydrazid wirkt als Inhibitor der Synthese von NukleinsÄuren und Proteinen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 123-33-1
Sample solution is provided at 25 µL, 10mM.
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Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[1][2].
Maleic hydrazide is used in agriculture-in despite its known effect as a mutagenic and clastogenic agent. Maleic hydrazide had lower IC50 values for all cell lines compared to Ethephon. Maleic hydrazide also showed least cytotoxicity on Vero cells, followed by Hep2 and HepG2 cells[3].
Maleic hydrazide has a low acute toxicity by oral, dermal, and inhalation routes of exposure[3].
[1]. Venezian A, et al. The Influence of the Plant Growth Regulator Maleic Hydrazide on Egyptian Broomrape Early Developmental Stages and Its Control Efficacy in Tomato under Greenhouse and Field Conditions. Front Plant Sci. 2017;8:691. Published 2017 May 16. [2]. Swietlińska Z, et al. Cytotoxic effects of maleic hydrazide. Mutat Res. 1978;55(1):15-30. [3]. Yurdakok B, et al. Cytotoxic effects of etephon and maleic hydrazide in Vero, Hep2, HepG2 cells. Drug Chem Toxicol. 2014;37(4):459-465.
| Cas No. | 123-33-1 | SDF | |
| Canonical SMILES | O=C1C=CC(NN1)=O | ||
| Formula | C4H4N2O2 | M.Wt | 112.09 |
| Löslichkeit | Storage | Store at -20°C | |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 8.9214 mL | 44.607 mL | 89.214 mL |
| 5 mM | 1.7843 mL | 8.9214 mL | 17.8428 mL |
| 10 mM | 0.8921 mL | 4.4607 mL | 8.9214 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.50%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)
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