Mefenamic acid D4 (Synonyms: C.I. 473-d4) |
| Katalog-Nr.GC61038 |
MefenaminsÄure D4 ist eine mit Deuterium markierte MefenaminsÄure.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1216745-79-7
Sample solution is provided at 25 µL, 10mM.
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Mefenamic acid D4 is a deuterium labeled Mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively[1][2].
[1]. Gierse JK, et al. Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase. Biochem J. 1995 Jan 15;305 (Pt 2):479-84. [2]. Hashemipour MA, et al. In Vitro Cytotoxic Effects of Celecoxib, Mefenamic Acid, Aspirin and Indometacin on Several Cells Lines. J Dent (Shiraz). 2016 Sep;17(3):219-25.
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