MitTx |
| Katalog-Nr.GC72247 |
MitTx ist ein Komplex, der aus MitTx-α und MitTx-β gebildet wird.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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MitTx is a complex formed by MitTx-α and MitTx-β. MitTx is an ASIC1 channel activator with EC50 values of 9.4 and 23 nM for ASIC1a and ASIC1b isoforms, respectively. MitTx is highly selective for ASIC1 isoforms at neutral pH. Under acidic conditions, MitTx greatly enhances proton-evoked ASIC2a channel activation.
References:
[1]. Bohlen CJ, et al. A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature. 2011 Nov 16;479(7373):410-4.
Review for MitTx
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for MitTx
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