ML381 |
| Katalog-Nr.GC70225 |
ML381 (VU0488130) ist ein hochselektiver mAChR M5 orthogonaler Antagonist (IC50,450 nM; Ki,340 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1623481-80-0
Sample solution is provided at 25 µL, 10mM.
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ML381 (0.2 mg/kg; i.v.; single) possesses an overall acceptable DMPK profile for pharmacodynamic studies in rat, with the exception of poor metabolic stability and a potential for amide hydrolysis in plasma; as such, ML381 is best suited to use as an in vitro/electrophysiological probe[1].
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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