MM41 |
Katalog-Nr.GC64591 |
MM41 ist ein potenter Stabilisator von menschlichen Telomer- und Genpromotor-DNA-Quadruplexen. MM41 ist stark gegen die Pankreaskrebs-Zelllinie MIA PaCa-2 mit einem IC50-Wert von <10 nM.
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Cas No.: 1429028-96-5
Sample solution is provided at 25 µL, 10mM.
MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC50 value of <10 nM[1].
[1]. Marialuisa Micco, et al. Structure-based design and evaluation of naphthalene diimide G-quadruplex ligands as telomere targeting agents in pancreatic cancer cells. J Med Chem
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