MPEG-2000-DSPE (Synonyms: 1,2-DSPE-MPEG(5000), Methyl-PEG2000-DSPE, MPEG-2000-DSPE) |
| Katalog-Nr.GC64095 |
MPEG-2000-DSPE ist ein Phospholipid-PEG-Konjugat, das sowohl hydrophil als auch hydrophob ist. MPEG-2000-DSPE wird bei der Synthese von Liposomen verwendet, erhÖht die Hydrophilie auf der OberflÄche von Liposomen und erhÖht folglich die Langlebigkeit von Liposomen im Blutkreislauf fÜr die Untersuchung von Antikrebs- und Antimalariamitteln.
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Cas No.: 147867-65-0
Sample solution is provided at 25 µL, 10mM.
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MPEG-2000-DSPE is a phospholipid PEG conjugate, has both hydrophilicity and hydrophobility. MPEG-2000-DSPE is used in the synthesis of liposomes, increases the hydrophilicity on the surface of liposomes, consequently increasing the longevity of liposomes in the blood circulation for the study of anticancer and antimalarial agents[1][2].
[1]. Rathore SS, et al. Effect of surface charge and density of distearylphosphatidylethanolamine-mPEG-2000 (DSPE-mPEG-2000) on the cytotoxicity of liposome-entrapped ricin: effect of lysosomotropic agents. Int J Pharm. 2008;350(1-2):79-94.
[2]. Hasan GM, et al. Inhibition of the Growth of Plasmodium falciparum in Culture by Stearylamine-Phosphatidylcholine Liposomes. J Parasitol Res. 2011;2011:120462.
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