MRGPRX1 agonist 1 |
| Katalog-Nr.GC63078 |
MRGPRX1-Agonist 1 ist ein hochpotenter Agonist von MRGPRX1 (Mas-related G-Protein-coupled receptor X1) mit einem EC50-Wert von 50 nM und ist gegenÜber MRGPRC11 inaktiv.
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Cas No.: 2377379-39-8
Sample solution is provided at 25 µL, 10mM.
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MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1), with an EC50 of 50 nM, and is inactive on MRGPRC11. Analgesic effect[1].
[1]. PrchalovÁ E, et al. Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists. J Med Chem. 2019 Sep 26;62(18):8631-8641.
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