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N4-Acetylsulfamethoxazole-d4

Katalog-Nr.GC72542

N4-Acetylsulfamethoxazole-d4 ist das Deuterium markierte N4-Acetylsulfamethoxazol.

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N4-Acetylsulfamethoxazole-d4 Chemische Struktur

Cas No.: 1215530-54-3

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5 mg
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
N4-Acetylsulfamethoxazole-d4 is the deuterium labeled N4-Acetylsulfamethoxazole. N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is a metabolite ofSulfamethoxazole . Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic, used for bacterial infections[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References:
[1]. https://pubchem.ncbi.nlm.nih.gov/compound/Acetylsulfamethoxazole
[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

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