Nav1.7-IN-2 |
| Katalog-Nr.GC31002 |
Nav1.7-IN-2 ist ein Inhibitor von spannungsgesteuerten NatriumkanÄlen (Nav), insbesondere Nav 1.7, mit einem IC50 von 80 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1332295-35-8
Sample solution is provided at 25 µL, 10mM.
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Nav1.7-IN-2 is an inhibitor of voltage-gated sodium channels (Nav), in particular Nav 1.7, with IC50 of 80 nM.IC50 value: 80 nMTarget: Nav 1.7Nav1.7-IN-2 is useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorder. The more detailed information please refer to WO 2011103196 A1. Nav1.7-IN-2 is a Nav1.7 channel inhibitor extracted from patent WO/2011103196 A1, compound example J, has an IC50 of 80 nM.
[1]. Bregman Howard, et al. Preparation of aryl carboxamide derivatives as sodium channel inhibitors for treatment of pain. From PCT Int. Appl. (2011), WO 2011103196 A1 20110825.
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