NBC 6 |
| Katalog-Nr.GC50611 |
NBC 6 ist ein potenter, selektiver NLRP3-Inflammasom-Inhibitor (IC50= 574 nM), der unabhÄngig von Ca2+ wirkt.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2068818-02-8
Sample solution is provided at 25 µL, 10mM.
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NLRP3 inflammasome inhibitor (IC50 = 574 nM). Inhibits nigericin-induced inflammasome activation in THP-1 cells and Imiquimod induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs).
Baldwin et al (2017) Boron-based inhibitors of the NLRP3 inflammasome. Cell Chem.Biol. 24 1321 PMID:28943355
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
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