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NP-1815-PX sodium

Katalog-Nr.GC71126

NP-1815-PX sodium ist ein potenter und selektiver P2X4R-Antagonist.

Products are for research use only. Not for human use. We do not sell to patients.

NP-1815-PX sodium Chemische Struktur

Cas No.: 1239578-80-3

Größe Preis Lagerbestand Menge
1 mg
108,00 $
Auf Lager
5 mg
279,00 $
Auf Lager
10 mg
450,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
NP-1815-PX sodium is a potent and selective P2X4R antagonist. NP-1815-PX sodium has anti-inflammatory activity, and can relieve pain in chronic pain models. NP-1815-PX sodium also inhibits guinea pig tracheal/bronchial smooth muscle (TSM and BSM) contractions.

References:
[1]. Matsumura Y, et al. A novel P2X4 receptor-selective antagonist produces anti-allodynic effect in a mouse model of herpetic pain. Sci Rep. 2016 Aug 31;6:32461.
[2]. Obara K, et al. Effects of NP-1815-PX, a P2X4 Receptor Antagonist, on Contractions in Guinea Pig Tracheal and Bronchial Smooth Muscles. Biol Pharm Bull. 2022;45(8):1158-1165.
[3]. D'Antongiovanni V, et al. Anti-inflammatory Effects of Novel P2X4 Receptor Antagonists, NC-2600 and NP-1815-PX, in a Murine Model of Colitis. Inflammation. 2022 Aug;45(4):1829-1847.

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