NP3-562 |
| Katalog-Nr.GC71499 |
NP3-562 ist ein potenter, oral aktiver, trizyklischer NLRP3-Inhibitor mit einem IC50 von 214 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2409825-32-5
Sample solution is provided at 25 µL, 10mM.
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NP3-562 is a potent, orally active, tricyclic NLRP3 Inhibitor, with an IC50 of 214 nM. NP3-562 (30 mg/kg, p.o.) inhibits IL-1β release in a mouse acute peritonitis model.
References:
[1]. Juraj Velcicky, et al. Discovery of Potent, Orally Bioavailable, Tricyclic NLRP3 Inhibitors. J Med Chem. 2024 Jan 4.
Review for NP3-562
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for NP3-562
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