Nrf2 activator-6 |
Katalog-Nr.GC71031 |
Nrf2 activator-6, eine Tetrahydroisochinolinverbindung, ist ein Nrf2-Aktivator.
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Cas No.: 2728780-74-1
Sample solution is provided at 25 µL, 10mM.
Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4).
Nrf2 activator-6 (Example 4) increases the mRNA level of NRF2 mediated gene NADPH:quinone acceptor oxidoreductase 1 (NQO1), with an EC50 of 0.3 nM[1].
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