Nudifloramide-d3 |
| Katalog-Nr.GC66377 |
Nudifloramid-d3 (2PY-d3) ist das mit Deuterium bezeichnete Nudifloramid. Nudifloramid (2PY) ist eines der Endprodukte des Abbaus von Nicotinamid-Adenin-Dinukleotid (NAD). Nudifloramid hemmt die AktivitÄt der Poly(ADP-Ribose)-Polymerase (PARP-1) in vitro signifikant.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1207384-48-2
Sample solution is provided at 25 µL, 10mM.
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Nudifloramide-d3 (2PY-d3) is the deuterium labeled Nudifloramide. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro[1].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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