Peramivir Trihydrate |
| Katalog-Nr.GC13110 |
Peramivir-Trihydrat (RWJ-270201-Trihydrat; BCX-1812-Trihydrat) ist ein hochwirksamer, selektiver und oral aktiver Hemmer der Influenzavirus-Neuraminidase (NA) mit IC50-Werten im Bereich von 0,9 bis 4,3 nM fÜr neun NA-Subtypen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1041434-82-5
Sample solution is provided at 25 µL, 10mM.
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Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes[1][2].
References:
[1]. Babu YS, et al. BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design. J Med Chem. 2000 Sep 21;43(19):3482-6.
[2]. Young D, et al. RWJ-270201 (BCX-1812): a novel neuraminidase inhibitor for influenza. Philos Trans R Soc Lond B Biol Sci. 2001 Dec 29;356(1416):1905-13.
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