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Perphenazine (Synonyms: NSC 150866, SCH 3940)

Katalog-Nr.GC12293

Perphenazin ist ein oral aktiver Dopaminrezeptor- und Histamin-1-Rezeptorantagonist mit Ki-Werten von 0,56 nM (D2), 0,43 nM (D3) bzw. 6 nM (5-HT2A).

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Perphenazine Chemische Struktur

Cas No.: 58-39-9

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Perphenazine is a typical antipsychotic drug, inhibits 5-HT2Areceptor, Alpha-1A adrenergic receptor, Dopamine receptor D2/D3, D2L receptor, and Histamine H1 receptor, with Ki values of 5.6, 10, 0.765/0.13, 3.4, and 8 nM, respectively.

References:
[1]. Richtand NM, et al. Dopamine and serotonin receptor binding and antipsychotic efficacy. Neuropsychopharmacology. 2007 Aug;32(8):1715-26.

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