PK14105 |
| Katalog-Nr.GC30398 |
PK14105 ist eine biologische Bewertung als potenzieller Radioligand fÜr PET-Untersuchungen von PBBS-Rezeptoren.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 107257-28-3
Sample solution is provided at 25 µL, 10mM.
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PK14105 is a biological evaluation as a potential radioligand for PET studies of PBBS receptors.in vivo binding experiments, in which PK 14105 was injected into rats with unilaterallylesioned striata, demonstrate that PK 14105 rapidly crosses the blood-brain-barrier and that thereis a marked retention of radioactivity in the lesioned striatum not seen in the unlesioned striatum or cerebellar vermis[1]It can also inhibit receptor ligands, calcium channel ligands and co-transporter in all salivary glands. [2]
[1]. Pascali C et al. The radiosynthesis of [18F]PK 14105 as an alternative radioligand for peripheral type benzodiazepine binding sites. Int J Rad Appl Instrum A. 1990;41(5):477-82. [2]. Franklin C. Wong et al. Affinity Labeling of Membrane Receptors Using Tissue-Penetrating Radiations. Biomed Res Int. 2013, 503095.
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