pNPS-DHA (Synonyms: CAY10741, Compound 59, DHA-nitrophenyl sulfonamide, p-Nitrophenyl sulfonamide Docosahexaenoic Acid) |
Katalog-Nr.GC47964 |
An anti-allergic DHEA derivative
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2454246-25-2
Sample solution is provided at 25 µL, 10mM.
pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1 It inhibits degranulation of RBL-2H3 mast cells (IC50 = 15 µM). pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice.
1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)
Average Rating: 5
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