PP-C8 |
Katalog-Nr.GC69730 |
PP-C8 ist ein wirksamer selektiver PROTAC-CDK12-Cyclin-K-Degradationshemmer. PP-C8 induziert den Abbau von CDK12-Cyclin K mit DC50-Werten von 416 bzw. 412 nM für CDK12 und Cyclin K. PP-C8 zeigt eine synergistische antiproliferative Wirkung in Triple-negativem Brustkrebs (TNBC) in Kombination mit PARP-Inhibitoren.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Review for PP-C8
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)Review for PP-C8
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