PPACK (hydrochloride) (Synonyms: Pebac; D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone; D-Phe-Pro-Arg-CH2Cl) |
Katalog-Nr.GC91433 |
PPACK ist ein synthetisches Peptidderivat, das irreversibel und spezifisch die thrombinvermittelte Aktivierung von Blutplättchen hemmt, indem es mit hoher Affinität an die aktive Stelle von Thrombin bindet (Ki = 0,24 nM).
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Cas No.: 82188-90-7
Sample solution is provided at 25 µL, 10mM.
PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM).1,2,3 It has been used as an anticoagulant (100 μM) and to study thrombin-mediated fibrin deposition, angiogenesis, and proinflammatory processes.4,5
Review for PPACK (hydrochloride)
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)Review for PPACK (hydrochloride)
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