Pronase E (Activity ≥ 7000 U/g) |
Katalog-Nr.GC30124 |
Pronase E (AktivitÄt ≥ 7000 U/g) ist eine Mischung aus proteolytischen Enzymen, die aus Streptomyces griseus gewonnen wird und Protein in einzelne AminosÄuren verdauen kÖnnte.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 9036-06-0
Sample solution is provided at 25 µL, 10mM.
Pronase E is a proteolytic enzyme mixture obtained from Streptomyces griseus[1]. It has the ability to break down proteins into individual amino acids, making it suitable for extensive protein degradation. It is used in various applications, including the study of protease inhibitors, thermal inactivation kinetics, nucleic acid isolation[2], tissue digestion in combination with collagenase and trypsin[3-5], and the purification of glycoproteins for glycopeptide production.
References:
[1]. Pronase E significantly increases the amount of most of the amino acids analysed ( PE vs C ) , especially Ile, His and Thr
[2]. Zhao W, Xu W, et,al. Key Amino Acid Residues of Mitochondrial Transcription Factor A Synergize with Abasic (AP) Site Dynamics To Facilitate AP-Lyase Reactions. ACS Chem Biol. 2023 May 19;18(5):1168-1179. doi: 10.1021/acschembio.3c00047. Epub 2023 Mar 17. PMID: 36930463; PMCID: PMC10198963.
[3]. Chen QT, Zhang ZY, et,al. HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma. Nat Metab. 2022 Oct;4(10):1306-1321. doi: 10.1038/s42255-022-00642-5. Epub 2022 Oct 3. PMID: 36192599; PMCID: PMC9584821.
[4]. Fang Z, Xu Y, et,al. Narirutin activates TFEB (transcription factor EB) to protect against Acetaminophen-induced liver injury by targeting PPP3/calcineurin. Autophagy. 2023 Aug;19(8):2240-2256. doi: 10.1080/15548627.2023.2179781. Epub 2023 Feb 24. PMID: 36779633; PMCID: PMC10351474.
[5]. Chen S, Li S, et,al. Caspase-mediated LPS sensing and pyroptosis signaling in Hydra. Sci Adv. 2023 Jul 21;9(29):eadh4054. doi: 10.1126/sciadv.adh4054. Epub 2023 Jul 21. PMID: 37478191; PMCID: PMC10361584.
Average Rating: 5
(Based on Reviews and 15 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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