Propargyl-PEG3-alcohol |
| Katalog-Nr.GC60304 |
Propargyl-PEG3-Alkohol ist ein PEG-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann.
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Cas No.: 208827-90-1
Sample solution is provided at 25 µL, 10mM.
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Propargyl-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Andrew P. Crew, et al. Brm targeting compounds and associated methods of use. US20190300521A1.
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