Propofol β-D-Glucuronide |
Katalog-Nr.GC18569 |
Propofol β-D-glucuronide is a metabolite of propofol sulfate , a short-acting anesthetic agent.
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Cas No.: 114991-26-3
Sample solution is provided at 25 µL, 10mM.
Propofol β-D-glucuronide is a metabolite of propofol sulfate , a short-acting anesthetic agent. [1] [2] The metabolite is generated through the glucuronidation of propofol by uridine diphosphate glucuronosyltransferases. Propofol metabolism appears to occur more rapidly in women than men. [1]
Reference:
[1]. Choong, E., Loryan, I., Lindqvist, M., et al. Sex difference in formation of propofol metabolites: A replication stud. Basic Clin.Pharmacol.Toxicol. 113(2), 126-131 (2013).
[2]. Sørensen, L.K., and Hasselstrøm, J.B. Simultaneous determination of propofol and its glucuronide in whole blood by liquid chromatography-electrospray tandem mass spectrometry and the influence of sample storage conditions on the reliability of the test results. J.Pharm.Biomed.Anal. 109, (2015).
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