ProTx II TFA |
| Katalog-Nr.GC72116 |
ProTx II TFA ist ein selektiver Blocker von Nav1,7-Natriumkanälen mit einem IC50 von 0,3 nM und ist mindestens 100-fach selektiv für Nav1,7 gegenüber anderen Natriumkanälen.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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References:
[1]. Tanaka K, et al. Antihyperalgesic effects of ProTx-II, a Nav1.7 antagonist, and A803467, a Nav1.8 antagonist, in diabetic mice. J Exp Pharmacol. 2015 Jun 24;7:11-6.
[2]. Schmalhofer WA, et al. ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors. Mol Pharmacol. 2008 Nov;74(5):1476-84.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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