Quinine (Synonyms: NSC 192949) |
| Katalog-Nr.GC41455 |
Chinin ist ein Alkaloid-Antimalariamittel, das MIC-Werte von 10 bis 500 nM für 60 thailändische Isolate von P. aufweist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 130-95-0
Sample solution is provided at 25 µL, 10mM.
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Quinine is an alkaloid antimalarial agent that has MIC values ranging from 10 to 500 nM for 60 Thai isolates of P. falciparum. It inhibits hemozoin formation in purified trophozoites, leading to an increase in free heme, similar to the mechanism of action of chloroquine . In mice, quinine reduces P. berghei parasite load in the blood with a minimum effective dose (MED) of 150 mg/kg. Formulations containing quinine have been used in the treatment of uncomplicated malaria.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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