R-(+)-Mono-desmethylsibutramine |
| Katalog-Nr.GC63508 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 229639-54-7
Sample solution is provided at 25 µL, 10mM.
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R-(+)-Mono-desmethylsibutramine is the R enantiomer of Mono-desmethylsibutramine.
Sibutramine, a monoamine reuptake inhibitor, is used as a racemate, for the treatment of obesity. It is converted in vivo mainly to two desmethyl active metabolites, mono-desmethylsibutramine (MDS) and di-desmethylsibutramine (DDS) [1].
[1]. Bae K, et al. Analysis of enantiomers of sibutramine and its metabolites in rat plasma by liquid chromatography-mass spectrometry using a chiral stationary-phase column. J Pharm Biomed Anal. 2009 Sep 8;50(2):267-70.
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