(R)-TTA-P2 |
Katalog-Nr.GC70204 |
(R)-TTA-P2 ist das Isomer von TTA-P2 und kann als experimentelle Kontrolle verwendet werden.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
(R)-TTA-P2 is the isomer of TTA-P2 , and can be used as an experimental control. TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease.
References:
[1]. Chemin J, et al. De novo mutation screening in childhood-onset cerebellar atrophy identifies gain-of-function mutations in the CACNA1G calcium channel gene. Brain. 2018;141(7):1998-2013.
Review for (R)-TTA-P2
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)Review for (R)-TTA-P2
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