(Rac)-E1R |
Katalog-Nr.GC38721 |
(Rac)-E1R (Verbindung 2) ist das Racemat von E1R.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 787623-60-3
Sample solution is provided at 25 µL, 10mM.
(Rac)-E1R (Compound 2) is the racemate of E1R. (Rac)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders[1].
Sigma-1 receptor plays an important role in neuronal plasticity, a process implicated in the pathophysiology of neuropsychiatric diseases, such as Alzheimer's disease, major depressive disorders, and schizophrenia[1].
[1]. Veinberg G, et al. Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor. Bioorg Med Chem. 2013 May 15;21(10):2764-71.
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