rac-Hesperetin-d3 (Synonyms: (±)-3',5,7-Trihydroxy-4'-methoxyflavanone-d3) |
| Katalog-Nr.GC49771 |
An internal standard for the quantification of hesperetin
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1346605-26-2
Sample solution is provided at 25 µL, 10mM.
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rac-Hesperetin-d3 is intended for use as an internal standard for the quantification of hesperetin by GC- or LC-MS. rac-Hesperetin is a racemic mixture of the flavanones (S)-hesperetin and (R)-hesperetin. rac-Hesperetin (1 mM) inhibits heat-induced advanced glycation end product formation between BSA and glucose by 56.7%.1 It also inhibits α-glucosidase and protein tyrosine phosphatase 1B (PTP1B; IC50s = 15.28 and 20.16 µM, respectively).2 rac-Hesperetin (100 µM) protects against hydrogen peroxide-induced cytotoxicity in MIN6 pancreatic beta cells by 72.27%.
1.Li, D., Mitsuhashi, S., and Ubukata, M.Protective effects of hesperidin derivatives and their stereoisomers against advanced glycation end-products formationPharm. Biol.50(12)1531-1535(2012) 2.Xu, J., Wang, X., Yue, J., et al.Polyphenols from acorn leaves (Quercus liaotungensis) protect pancreatic beta cells and their inhibitory activity against α-glucosidase and protein tyrosine phosphatase 1BMolecules23(9)2167(2018)
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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