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RBP4 inhibitor 1

Katalog-Nr.GC70877

RBP4 inhibitor 1 (Verbindung 43b) ist ein potenter und oral aktiver Retinol-bindender Protein 4 (RBP4)-Inhibitor mit IC50s von 28 nM und 110 nM für Mensch und Maus RBP4.

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RBP4 inhibitor 1 Chemische Struktur

Cas No.: 1198180-03-8

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5 mg
216,00 $
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10 mg
342,00 $
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25 mg
684,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice.

References:
[1]. Shinji Nakamura, et al. Discovery of phenylpyrrolidine derivatives as a novel class of retinol binding protein 4 (RBP4) reducers. Bioorg Med Chem. 2022 Jan 15;54:116553.

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