RDN2150 TFA |
| Katalog-Nr.GC71364 |
RDN2150 TFA ist ein ZAP-70-Hemmer (IC50: 14.6 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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RDN2150 (Compound 25) TFA is a ZAP-70 inhibitor (IC50: 14.6 nM). RDN2150 TFA covalently binds to the C346 residue of ZAP-70. RDN2150 TFA inhibits the expression of CD25 and CD69, and inhibits CD4+ T cell activation. RDN2150 TFA can be used for research of psoriasis.
References:
[1]. Rao D, et al. Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis. J Med Chem. 2023 Aug 18.
Review for RDN2150 TFA
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for RDN2150 TFA
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