CCR6 inhibitor 1 |
| Katalog-Nr.GC34521 |
CCR6-Inhibitor 1 ist ein potenter und selektiver CCR6-Inhibitor mit IC50-Werten von 0,45 und 6 nM fÜr Affen- und Human-CCR6, viel selektiver bei CCR6 gegenÜber humanem CCR1 (IC50, > 30000 nM) und CCR7 (IC50, 9400 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2437547-04-9
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer[1]. Moneky CCR6|0.45 nM (IC50)|Human CCR6|6 nM (IC50)|Human CCR7|9400 nM (IC50)
CCR6 inhibitor 1 (Compound 35) inhibits L20-induced human B cell migration[1].
[1]. Tawaraishi T, et al. Identification of a novel series of potent and selective CCR6 inhibitors as biological probes. Bioorg Med Chem Lett. 2018 Oct 1;28(18):3067-3072.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *