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Barnidipine

Katalog-Nr.GC35469

Barnidipin (Mepirodipin) ist ein L-Typ-Calciumantagonist (CaA) mit hoher AffinitÄt zu [3H]-Initrendipin-Bindungsstellen (Ki=0,21 nmol/l) und hat eine selektive Wirkung gegen CaA-Rezeptoren.

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Barnidipine Chemische Struktur

Cas No.: 104713-75-9

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Barnidipine (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors[1].Barnidipine (Mepirodipine) is an antihypertensive drug and acts by the reduction of peripheral vascular resistance secondary to its vasodilatory action[2]. Ki: 0.21 nmol/l ([3H] initrendipine)[1]

[1]. van Zwieten PA, et al. Pharmacological profile of barnidipine: a single optical isomer dihydropyridine calcium antagonist. Blood Press Suppl. 1998;1:5-8 [2]. Malhotra HS, et al. Barnidipine. Drugs. 2001;61(7):989-96; discussion 997-8.

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