E3 ligase Ligand 11 (Synonyms: E3 ligase Ligand 11) |
| Katalog-Nr.GC35925 |
E3-Ligase-Ligand 11 ist der auf LCL161-Derivat basierende IAP-Ligand. E3-Ligase-Ligand 11 kann mit dem ABL-Liganden fÜr Protein durch einen Linker verbunden werden, um SNIPER zu bilden.
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Cas No.: 2357114-70-4
Sample solution is provided at 25 µL, 10mM.
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E3 ligase Ligand 13 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 13 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
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